Nano mechanical autonomy is a rising development field making machines or robots whose parts are at or near the measure of a nanometer (10?9 meters). More especially, Nano mechanical autonomy (rather than small scale apply autonomy) suggests the nanotechnology building request of arranging and building Nano robots, with contraptions reaching out in estimate from 0.1– 10 micrometers and created of nanoscale or sub-nuclear fragments. The terms nanobot, nanoid, nanite, nanomachine, or nanomite have in like manner been used to depict such contraptions at display under imaginative work.Nano machines are by and large in the creative work arrange, however some primitive sub-nuclear machines and nanomotors have been attempted. An outline is a sensor having a switch around 1.5 nanometers over, prepared to incorporate specific particles a substance test. The vital profitable employments of Nano machines may be in Nano solution. For example, natural machines could be used to perceive and wreck threat cells. Another potential application is the acknowledgment of hurtful chemicals, and the estimation of their obsessions, in the earth. Rice University has displayed a single molecule auto made by a compound method and including buckminsterfullerene (Bucky balls) for wheels. It is enacted by controlling the environmental temperature and by arranging a looking at tunneling amplifying focal point tip.